Changes In Magnetic Nanoparticle Size In Different Cell Growth Media
School Name
Governor's School for Science & Mathematics
Grade Level
12th Grade
Presentation Topic
Microbiology
Presentation Type
Mentored
Abstract
Magnetic Nanoparticles (MNPs) are small metallic particles that can be heated up by exposing them to an Alternating Magnetic Field. These nanoparticles can be targeted to specific cells (such as cancer or bacteria), and eventually the cells are killed through magnetic hyperthermia. For these particles to be effective they must be small enough to remain undetected by the body’s immune system. A diameter of 200 nm or less is preferred. While the MNPs are usually under 100 nm initially, interactions with the proteins in the body can alter the size and chemistry, changing the inherent properties of the MNPs. This presents a serious engineering challenge, and in order to make more stable particles, the factors contributing to their instability must be initially understood.
Recommended Citation
Stokes, Jacob, "Changes In Magnetic Nanoparticle Size In Different Cell Growth Media" (2017). South Carolina Junior Academy of Science. 156.
https://scholarexchange.furman.edu/scjas/2017/all/156
Location
Wall 224
Start Date
3-25-2017 12:00 PM
Presentation Format
Oral and Written
Group Project
No
Changes In Magnetic Nanoparticle Size In Different Cell Growth Media
Wall 224
Magnetic Nanoparticles (MNPs) are small metallic particles that can be heated up by exposing them to an Alternating Magnetic Field. These nanoparticles can be targeted to specific cells (such as cancer or bacteria), and eventually the cells are killed through magnetic hyperthermia. For these particles to be effective they must be small enough to remain undetected by the body’s immune system. A diameter of 200 nm or less is preferred. While the MNPs are usually under 100 nm initially, interactions with the proteins in the body can alter the size and chemistry, changing the inherent properties of the MNPs. This presents a serious engineering challenge, and in order to make more stable particles, the factors contributing to their instability must be initially understood.
Mentor
Mentor: Tzuen-Rong Tzeng, Clemson University