Improving the Design of Prosthetic Veins

Alexandra Grant, Center for Advanced Technical Studies

Abstract

Prosthetic veins are used to replaced damaged venous tissue when venous return is not equal to cardiac output. Chronic venous insufficiency (CVI) and varicose veins are two conditions where there is a great disparity between venous return and cardiac output due to damage to the venous tissue as well as the venous valves that prevent retrograde blood flow. Current prosthetic veins do not have valves in them, so the objective of this project was to design a prosthetic vein with valves in case doing so would help prolong graft life and vascular health in patients. In this project, a prosthetic venous valve was 3D printed using a flexible, porous filament. The prosthetic vein was then placed and secured in a prosthetic vein, which was tested using a peristaltic pump and evaluated through input-to-output ratios. The input of the system would be analogous to the cardiac output, and the output of the system would be analogous to venous return. Keywords Prosthetic veins Chronic Venous Insufficiency Vascular graft

 
Mar 25th, 12:00 PM

Improving the Design of Prosthetic Veins

Wall 321

Prosthetic veins are used to replaced damaged venous tissue when venous return is not equal to cardiac output. Chronic venous insufficiency (CVI) and varicose veins are two conditions where there is a great disparity between venous return and cardiac output due to damage to the venous tissue as well as the venous valves that prevent retrograde blood flow. Current prosthetic veins do not have valves in them, so the objective of this project was to design a prosthetic vein with valves in case doing so would help prolong graft life and vascular health in patients. In this project, a prosthetic venous valve was 3D printed using a flexible, porous filament. The prosthetic vein was then placed and secured in a prosthetic vein, which was tested using a peristaltic pump and evaluated through input-to-output ratios. The input of the system would be analogous to the cardiac output, and the output of the system would be analogous to venous return. Keywords Prosthetic veins Chronic Venous Insufficiency Vascular graft