Chemical measurements in Drosophila
Makos, M. A.; Kuklinski, N. J.; Berglund, E. C.; Heien, M. L.; Ewing, A. G. Chemical Measurements in Drosophila. Trends Analyt. Chem. 2009, 28 (11), 1223–1234.
The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry and technologies involving intact organisms, including in vivo electrochemistry.
Trends Analyt. Chem.