Title

Quantitative Surface Plasmon Resonance Imaging: A Simple Approach to Automated Angle Scanning

ACS Citation

Ruemmele, J.A.; Golden, M.S.; Gao, Y.; Cornelius, E.M.; Anderson, M.E.; Postelnicu, L.; Georgiadis, R.M. Quantitative Surface Plasmon Resonance Imaging: A Simple Approach to Automated Angle Scanning. Anal. Chem.2008,80, 4752-4756.

Abstract

Here we present an automated angle-scanning surface plasmon resonance imaging (SPRi) instrument which provides multiplexed, quantitative reflectance data over a wide angular range. Angle-dependent artifacts, which arise from the simple optical setup, are corrected using software. This enables monitoring of significantly different surface coatings in many solvents, which would be outside the dynamic range of typical fixed-angle instruments. Operation in the visible to near-infrared range without the need for reconfiguration extends the instrument capabilities to increase sensitivity or to investigate the optical properties of surface films. This instrument provides maximum flexibility to study a wide range of systems with full exploitation of the quantitative capabilities of SPRi achieved by fitting data to the Fresnel model.

Source Name

Analytical Chemistry

Publication Date

5-14-2008

Volume

80

Issue

12

Page(s)

4752-4756

Document Type

Citation

Citation Type

Article

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