Title

Macrophage Polarization in th Aorta Following IL-6 Infusion

Author(s)

Joseph Ebai, GSSM

School Name

Governor's School for Science and Mathematics

Grade Level

12th Grade

Presentation Topic

Cell and Molecular Biology

Presentation Type

Mentored

Abstract

The goal of this summer research was to establish the prevalence of pro-inflammatory and anti-inflammatory macrophages in the aortic ring samples of mice that were infused with Interleukin-6. Furthermore, this research could possibly give more insight into the signals that initiate and promote aneurysm growth in humans that are afflicted with abdominal aortic aneurysms, also known as AAA. Through the use of antigen retrieval and immunohistochemistry, results were obtained, but the results were contrary to what was expected.

Location

Neville theater

Start Date

4-14-2018 11:45 AM

Presentation Format

Oral and Written

COinS
 
Apr 14th, 11:45 AM

Macrophage Polarization in th Aorta Following IL-6 Infusion

Neville theater

The goal of this summer research was to establish the prevalence of pro-inflammatory and anti-inflammatory macrophages in the aortic ring samples of mice that were infused with Interleukin-6. Furthermore, this research could possibly give more insight into the signals that initiate and promote aneurysm growth in humans that are afflicted with abdominal aortic aneurysms, also known as AAA. Through the use of antigen retrieval and immunohistochemistry, results were obtained, but the results were contrary to what was expected.