Is LPA Receptor 1 Used By Retinal Ganglion Cells to Find their Correct Connection In the Brain?
Abstract
For my research I was involved in investigating the role of LPA receptor one in the LPA signaling process in chicken embryos. To investigate this I dissected embryonic chickens for their retinal ganglion cells, treating them with the inhibitor (AM-095) and LPA, and later staining them to count how many growth cones had collapsed. If LPA receptor one was not in use during the LPA signalling process, the proportion of collapsed growth cones in dishes treated with the inhibitor and those without would be approximately the same. When the results of both dishes were graphed it was seen that the proportions were in fact the same and so it could be concluded that LPA receptor one does not play a part in the LPA signalling process in the embryonic stages of chicken development.
Is LPA Receptor 1 Used By Retinal Ganglion Cells to Find their Correct Connection In the Brain?
Founders Hall 142 A
For my research I was involved in investigating the role of LPA receptor one in the LPA signaling process in chicken embryos. To investigate this I dissected embryonic chickens for their retinal ganglion cells, treating them with the inhibitor (AM-095) and LPA, and later staining them to count how many growth cones had collapsed. If LPA receptor one was not in use during the LPA signalling process, the proportion of collapsed growth cones in dishes treated with the inhibitor and those without would be approximately the same. When the results of both dishes were graphed it was seen that the proportions were in fact the same and so it could be concluded that LPA receptor one does not play a part in the LPA signalling process in the embryonic stages of chicken development.
