Title

Antibiotics and Cellular Proliferation in Infected Burn wounds

School Name

Chapin High School

Grade Level

11th Grade

Presentation Topic

Cell and Molecular Biology

Presentation Type

Non-Mentored

Abstract

Research will be conducted on the effect of antibiotics used to treat a S. aureus-caused infection on the rate of cellular proliferation in Burn Wounds. A burn wound that compromises the skin barrier allows for pathogens to enter and triggers the body’s immunosuppression response. This response inhibits or completely prevents the immune system of an individual from resisting any pathogens that may enter the body, causing the incidence of infection in burn victims to be high. The antibiotics used to treat these infections have been found to affect the proliferation rate of stem cells when used to isolate a cell culture. In burn victims, wound healing time is especially important to quickly cover the open and compromised skin barrier, to prevent other infections. If, due to the antibiotics used to treat a primary infection, the wound takes more time to heal, a secondary infection is more likely. Unlike other studies, this study will use the antibiotics as the independent variable and will use earthworms to simulate burns using hot metal, and make a connection between these burns in earthworms to burns in humans. By testing the proliferation rate of the via samples taken from the worms in the antibiotics and with Staphylococcus aureus, it is possible to find if antibiotics affect the wound healing time in burn victims with Staphylococcus aureus.

Location

ECL 103

Start Date

3-25-2023 10:15 AM

Presentation Format

Oral and Written

Group Project

No

COinS
 
Mar 25th, 10:15 AM

Antibiotics and Cellular Proliferation in Infected Burn wounds

ECL 103

Research will be conducted on the effect of antibiotics used to treat a S. aureus-caused infection on the rate of cellular proliferation in Burn Wounds. A burn wound that compromises the skin barrier allows for pathogens to enter and triggers the body’s immunosuppression response. This response inhibits or completely prevents the immune system of an individual from resisting any pathogens that may enter the body, causing the incidence of infection in burn victims to be high. The antibiotics used to treat these infections have been found to affect the proliferation rate of stem cells when used to isolate a cell culture. In burn victims, wound healing time is especially important to quickly cover the open and compromised skin barrier, to prevent other infections. If, due to the antibiotics used to treat a primary infection, the wound takes more time to heal, a secondary infection is more likely. Unlike other studies, this study will use the antibiotics as the independent variable and will use earthworms to simulate burns using hot metal, and make a connection between these burns in earthworms to burns in humans. By testing the proliferation rate of the via samples taken from the worms in the antibiotics and with Staphylococcus aureus, it is possible to find if antibiotics affect the wound healing time in burn victims with Staphylococcus aureus.