DNA-templated Ag nanocluster formation

ACS Citation

Petty, J. T.; Zheng, J.; Hud, N. V.; Dickson, R. M. DNA-templated Ag nanocluster formation. J. Am. Chem. Soc. 2004, 126, 5207-12.

Abstract

The high affinity of Ag+ for DNA bases has enabled creation of short oligonucleotide-encapsulated Ag nanoclusters without formation of large nanoparticles. Time-dependent formation of cluster sizes ranging from Ag1 to Ag4/oligonucleotide were observed with strong, characteristic electronic transitions between 400 and 600 nm. The slow nanocluster formation kinetics enables observation of specific aqueous nanocluster absorptions that evolve over a period of 12 h. Induced circular dichroism bands confirm that the nanoclusters are associated with the chiral ss-DNA template. Fluorescence, absorption, mass, and NMR spectra all indicate that multiple species are present, but that their creation is both nucleotide- and time-dependent.

Source Name

Journal of the American Chemical Society

Publication Date

1-1-2004

Volume

126

Issue

16

Page(s)

1155-1167

Document Type

Citation

Citation Type

Article

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