Title

Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide

ACS Citation

Kersten, K.M.; Breen, M.E.; Mapp, A.K.; Matzger, A.J. Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide. Chem. Commun. (Cambridge, U. K.) 2018, 54, 9286-9289.

Abstract

Antimicrobial functionality is introduced into a pharmaceutical formulation of miconazole while improving solubility. The work leverages hydrate formation propensity in order to produce hydrogen peroxide solvates. The ubiquity of hydrate formation suggests that hydrogen peroxide can be broadly deployed in pharmaceuticals, rendering a liquid excipient suitable for solid pharmaceutical formulations.

Source Name

Chemical Communications

Publication Date

7-26-2018

Issue

54

Page(s)

9286-9289

Document Type

Citation

Citation Type

Article

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