Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide
ACS Citation
Kersten, K.M.; Breen, M.E.; Mapp, A.K.; Matzger, A.J. Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide. Chem. Commun. (Cambridge, U. K.) 2018, 54, 9286-9289.
Version of Record
Abstract
Antimicrobial functionality is introduced into a pharmaceutical formulation of miconazole while improving solubility. The work leverages hydrate formation propensity in order to produce hydrogen peroxide solvates. The ubiquity of hydrate formation suggests that hydrogen peroxide can be broadly deployed in pharmaceuticals, rendering a liquid excipient suitable for solid pharmaceutical formulations.
Source Name
Chemical Communications
Publication Date
7-26-2018
Issue
54
Page(s)
9286-9289
Document Type
Citation
Citation Type
Article
COinS