Probing Composition Effects on the Intrinsic Energetics of Proton Transfer in Binary (HCl)m(H2O)n Clusters

ACS Citation

Tucker, M.R.; Arradondo, S.N.; Longsworth, O.M.; Shields, G.C.; Tschumper, G.S. Probing Composition Effects on the Intrinsic Energetics of Proton Transfer in Binary. ChemPhysChem, 2026, 27, e202500920. DOI: /10.1002/cphc.202500920

Abstract

This work examines the effects on intrinsic energetics as the composition of finite (HCl)m(H2O)n cluster families containing at least one water molecule is changed at the molecular level, where m ≥ 2 and m + n = 4 − 6, and the associated (Cl−)x(H3O+)x(HCl)mx(H2O)nx clusters resulting from the dissociation of x HCl fragments via proton transfer (PT). They are collectively labeled m:n, and xPT indicates the degree of dissociation, from 0PT (no dissociation) up to 3PT. More than 1000 unique minima were identified via ωB97X-D/6-31++G(d,p) optimizations and frequency computations. Of those, nearly 500 lie within 5 kcal mol−1 of the corresponding lowest-energy minimum structure as determined by CCSD(T)-F12/haTZ-F12 single point energies: 25 for the 2:2 and 3:1 tetramers, 127 for the 2:3, 3:2, and 4:1 pentamers, and 333 for the 2:4, 3:3, 4:2, and 5:1 hexamers. In four of the nine m:n systems examined (2:2, 3:1, 4:1, 5:1), no low-energy minima exhibited PT, but the other five (2:3, 3:2, 2:4, 3:3, 4:2) have 1PT and 2PT structures with electronic energies near or below the lowest-energy 0PT configurations. In the 2:4, 3:3, and 4:2 hexamers, for example, at least one 1PT structure lies ≈4, 3, and 0.5  kcal mol−1 below the lowest-energy 0PT structures, respectively, based on CCSD(T)-F12 electronic energies.

Source Name

ChemPhysChem

Publication Date

Spring 4-25-2026

Volume

27

Page(s)

e202500920

Document Type

Citation

Citation Type

Article

Disciplines

Chemistry

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