"Enzymatic Reductions with Dihydrogen via Metal Catalyzed Cofactor Rege" by Robert T. Hembre, Paul S. Wagenknecht et al.
 

Enzymatic Reductions with Dihydrogen via Metal Catalyzed Cofactor Regeneration

ACS Citation

Hembre, R. T.; Wagenknecht, P. S.; Penney, J. M. Enzymatic Reductions with Dihydrogen via Metal Catalyzed Cofactor Regeneration. U.S. Patent 6,599,723, July 29, 2003.

Abstract

The invention provides a process for reducing an unsaturated organic compound, comprising mixing the unsaturated organic compound and H2 in the presence of a catalyst to form a reduced organic product, wherein the catalyst comprises: a) at least one metal salt or complex, b) at least one nicotinamide cofactor; and c) a nicotinamide cofactor dependent enzyme, wherein: i) when the metal salt or complex is a platinum carbonyl cluster complex, the catalyst does not comprise a redox active dye; and ii) when the metal salt or complex is a rhodium phosphine complex, the nicotinamide cofactor dependent enzyme is not a mixture of horse liver alcohol dehydrogenase and lactate dehydrogenase.

Publication Date

1-1-2003

Page(s)

7376-7376

Document Type

Citation

Citation Type

Patent

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