Higher-order DNA constructs for silver clusters

Author(s)

Dahye KimFollow

Department, Center, or Institute

Chemistry

Presentation Format

Poster

Presentation Type

On-campus research

Description

DNA strands host specific silver clusters that are highly emissive chromophores. Our studies focus on how these metallic ligands perturb the structure of their DNA hosts. A composite oligonucleotide has two components: a 5’- adenine cluster domain that complexes silver clusters and a 3’-cytosine region. The complex was studies by varying the DNA sequences, the amounts of silver, and the reaction conditions. Mass spectrometry was used to measure the silver and DNA stoichiometries in the resulting complexes.

Session Number

5

Start Date and Time

4-9-2019 4:00 PM

Location

PAC Gym

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Apr 9th, 4:00 PM

Higher-order DNA constructs for silver clusters

PAC Gym

DNA strands host specific silver clusters that are highly emissive chromophores. Our studies focus on how these metallic ligands perturb the structure of their DNA hosts. A composite oligonucleotide has two components: a 5’- adenine cluster domain that complexes silver clusters and a 3’-cytosine region. The complex was studies by varying the DNA sequences, the amounts of silver, and the reaction conditions. Mass spectrometry was used to measure the silver and DNA stoichiometries in the resulting complexes.