Title
The Comorbidity of PTSD and Alcohol Consumption with the Use of a D3 Antagonist
Department, Center, or Institute
Biology
Secondary Department, Center, or Institute
Neuroscience
Presentation Format
Department Organized Oral Session
Presentation Type
On-campus research
Description
Post-Traumatic Stress Disorder (PTSD) is a disorder in which people who suffered from a tragic even and have difficulty recovering after such an event. Veterans that have gone to war and rape victims are a few examples of individuals that experience PTSD. The research that this experiment conducted was to better understand the disorder and find a potential solution. We induced PTSD like symptoms in Sprague Dawley rats using a modified version of the SPS model, then injected them with a D3 antagonist to see if it would decrease their alcohol consumption. The results were significant in that the SPS model did induced PTSD-like symptoms to the rats, but no significance was seen in the SPS rats pressing more compared to the control rats in the FR1 and FR4 schedules or during injections. The results are not consistent with past studies in that the D3 antagonist had no effect on the rats alcohol consumption.
Department Organized Oral Session Title
Neuroscience Program Talks Session I
Moderator/Professor
David Hollis, Biology and Neuroscience
Session Number
1
Start Date and Time
4-9-2019 9:45 AM
Location
Johns Hall 208
Recommended Citation
Sarhan, Mutaz, "The Comorbidity of PTSD and Alcohol Consumption with the Use of a D3 Antagonist" (2019). Furman Engaged!. 479.
https://scholarexchange.furman.edu/furmanengaged/2019/all/479
The Comorbidity of PTSD and Alcohol Consumption with the Use of a D3 Antagonist
Johns Hall 208
Post-Traumatic Stress Disorder (PTSD) is a disorder in which people who suffered from a tragic even and have difficulty recovering after such an event. Veterans that have gone to war and rape victims are a few examples of individuals that experience PTSD. The research that this experiment conducted was to better understand the disorder and find a potential solution. We induced PTSD like symptoms in Sprague Dawley rats using a modified version of the SPS model, then injected them with a D3 antagonist to see if it would decrease their alcohol consumption. The results were significant in that the SPS model did induced PTSD-like symptoms to the rats, but no significance was seen in the SPS rats pressing more compared to the control rats in the FR1 and FR4 schedules or during injections. The results are not consistent with past studies in that the D3 antagonist had no effect on the rats alcohol consumption.