Comparison of the Diffusion of Acetaminophen by its Forms
School Name
Southside High School
Grade Level
12th Grade
Presentation Topic
Biochemistry
Presentation Type
Non-Mentored
Abstract
In the human body, the manner in which a substance flows through the body hinge on the properties of both the substance in motion and the material through which it travels. For example, in the ingestion of certain pharmaceutical ones, peristalsis can be either propelled or hindered by the form in which the drug is ingested. This experiment accordingly measures the diffusion of acetaminophen across its constituent forms–capsules, tablets, and liquids. To most accurately emulate the pharmacokinetics present in the human body, we used dialysis tubing to serve as the medium for the flow, and change in the measure of the acetaminophen’s concentration will reflect the rate of diffusion. We hypothesize that the liquid form will diffuse at the fastest rate while the capsule form will disperse most slowly.
Recommended Citation
Lindberg, Jane and Bafna, Vaibhav, "Comparison of the Diffusion of Acetaminophen by its Forms" (2015). South Carolina Junior Academy of Science. 131.
https://scholarexchange.furman.edu/scjas/2015/all/131
Start Date
4-11-2015 8:30 AM
End Date
4-11-2015 8:45 AM
Comparison of the Diffusion of Acetaminophen by its Forms
In the human body, the manner in which a substance flows through the body hinge on the properties of both the substance in motion and the material through which it travels. For example, in the ingestion of certain pharmaceutical ones, peristalsis can be either propelled or hindered by the form in which the drug is ingested. This experiment accordingly measures the diffusion of acetaminophen across its constituent forms–capsules, tablets, and liquids. To most accurately emulate the pharmacokinetics present in the human body, we used dialysis tubing to serve as the medium for the flow, and change in the measure of the acetaminophen’s concentration will reflect the rate of diffusion. We hypothesize that the liquid form will diffuse at the fastest rate while the capsule form will disperse most slowly.