The Effectiveness Of Electrode Placement During Paired Associative Stimulation
School Name
Governor's School for Science and Math
Grade Level
12th Grade
Presentation Topic
Psychology and Sociology
Presentation Type
Mentored
Oral Presentation Award
1st Place
Written Paper Award
2nd Place
Abstract
Paired Associative Stimulation (PAS) is a relatively new technique in which a peripheral stimulation is paired with centrally applied transcranial magnetic stimulation (TMS), which produces plasticity, as measured by TMS motor evoked potential (MEPs). During standard PAS treatment, TMS is timed with median nerve stimulation (a pulse sent to two electrodes placed one centimeter apart on the median nerve) to produce an increased excitability in parts of the brain. The hypothesis that higher levels of excitability in the brain can be seen after PAS is performed with an electrode placed on an acupuncture point (Hegu) instead of the two median nerve electrodes was tested. Multiple subjects were put through standard PAS and acupoint-PAS in order to observe the levels of excitability created by both types of PAS treatment. It was found that the hypothesis was not supported and acupoint-PAS is less effective at exciting the brain than standard-PAS treatment.
Recommended Citation
Seigler, Samuel, "The Effectiveness Of Electrode Placement During Paired Associative Stimulation" (2016). South Carolina Junior Academy of Science. 118.
https://scholarexchange.furman.edu/scjas/2016/all/118
Location
Owens 108
Start Date
4-16-2016 9:45 AM
The Effectiveness Of Electrode Placement During Paired Associative Stimulation
Owens 108
Paired Associative Stimulation (PAS) is a relatively new technique in which a peripheral stimulation is paired with centrally applied transcranial magnetic stimulation (TMS), which produces plasticity, as measured by TMS motor evoked potential (MEPs). During standard PAS treatment, TMS is timed with median nerve stimulation (a pulse sent to two electrodes placed one centimeter apart on the median nerve) to produce an increased excitability in parts of the brain. The hypothesis that higher levels of excitability in the brain can be seen after PAS is performed with an electrode placed on an acupuncture point (Hegu) instead of the two median nerve electrodes was tested. Multiple subjects were put through standard PAS and acupoint-PAS in order to observe the levels of excitability created by both types of PAS treatment. It was found that the hypothesis was not supported and acupoint-PAS is less effective at exciting the brain than standard-PAS treatment.
Mentor
Mentor: Dr. Li; Institute of Psychiatry, Medical University of South Carolina