The Effect Of Di(2-Ethylhexyl) Adipate (Deha) On The Average Fertility Of Subsequent Generations Of Danio Rerio /
School Name
Dutch Fork High School
Grade Level
12th Grade
Presentation Topic
Biochemistry
Presentation Type
Non-Mentored
Abstract
Phthalates and phthalate substitutes can leach from disposable water bottles, contaminating the water within with chemicals that disrupt endocrine systems and negatively affect reproductivity (Sax 2011). In this study, we will investigate subsequent generations of Danio rerio and the effect that the common phthalate substitute and non-FDA regulated toxin, Di(2-ethylhexyl) Adipate (DEHA), has on the production of offspring by using a mature fish to viable offspring ratio to quantify our results. We expect to see a decrease in the rate of production of offspring in subsequent generations of zebrafish as DEHA concentration increases in the water supply. This study is crucial to the safety of Americans due to the genome of Danio rerio is 80% similar to humans (Barbazuk); therefore, the adverse effects on its fertility will be comparable to that of a human exposed to this same chemical. /
Recommended Citation
Ranta, Josh and Zhao, Richard, "The Effect Of Di(2-Ethylhexyl) Adipate (Deha) On The Average Fertility Of Subsequent Generations Of Danio Rerio /" (2016). South Carolina Junior Academy of Science. 183.
https://scholarexchange.furman.edu/scjas/2016/all/183
Location
Owens 204
Start Date
4-16-2016 8:45 AM
The Effect Of Di(2-Ethylhexyl) Adipate (Deha) On The Average Fertility Of Subsequent Generations Of Danio Rerio /
Owens 204
Phthalates and phthalate substitutes can leach from disposable water bottles, contaminating the water within with chemicals that disrupt endocrine systems and negatively affect reproductivity (Sax 2011). In this study, we will investigate subsequent generations of Danio rerio and the effect that the common phthalate substitute and non-FDA regulated toxin, Di(2-ethylhexyl) Adipate (DEHA), has on the production of offspring by using a mature fish to viable offspring ratio to quantify our results. We expect to see a decrease in the rate of production of offspring in subsequent generations of zebrafish as DEHA concentration increases in the water supply. This study is crucial to the safety of Americans due to the genome of Danio rerio is 80% similar to humans (Barbazuk); therefore, the adverse effects on its fertility will be comparable to that of a human exposed to this same chemical. /
