Title

Glyphosate and the increased prevalence of autism

Author(s)

Parth Patel, GSSM

School Name

Governor's School for Science and Mathematics

Grade Level

12th Grade

Presentation Topic

Cell and Molecular Biology

Presentation Type

Mentored

Abstract

The Increased prevalence of Autism Spectrum Disorder (ASD) is often correlated with the heighten use of glyphosate. Glyphosate is used as an herbicide, but it also doubles as an antibiotic. This chemical finds its way into our diet and harms our nerve cells via the release of a compound known as Lipopolysaccharides (LPS). LPS is released from the bacterial lysis that glyphosate causes in the gut flora, as LPS is found of the cell walls of gram negative bacteria. The hypothesis was that secretions from bacteria exposed to glyphosate (experimental group) would cause more axonal degeneration in the nerve cells as opposed to secretions from bacteria regularly grown in medium (control group). The 2266 (female) and 2267 (male) neuroblastoma cell lines were used to test the hypothesis. In the experimental groups, the secretions of bacteria exposed to glyphosate caused more axonal degeneration than the control group. Although Glyphosate cannot be directly called an environmental cause of ASD, it definitely caused axonal damage.

Location

Neville theater

Start Date

4-14-2018 10:45 AM

Presentation Format

Oral and Written

COinS
 
Apr 14th, 10:45 AM

Glyphosate and the increased prevalence of autism

Neville theater

The Increased prevalence of Autism Spectrum Disorder (ASD) is often correlated with the heighten use of glyphosate. Glyphosate is used as an herbicide, but it also doubles as an antibiotic. This chemical finds its way into our diet and harms our nerve cells via the release of a compound known as Lipopolysaccharides (LPS). LPS is released from the bacterial lysis that glyphosate causes in the gut flora, as LPS is found of the cell walls of gram negative bacteria. The hypothesis was that secretions from bacteria exposed to glyphosate (experimental group) would cause more axonal degeneration in the nerve cells as opposed to secretions from bacteria regularly grown in medium (control group). The 2266 (female) and 2267 (male) neuroblastoma cell lines were used to test the hypothesis. In the experimental groups, the secretions of bacteria exposed to glyphosate caused more axonal degeneration than the control group. Although Glyphosate cannot be directly called an environmental cause of ASD, it definitely caused axonal damage.