The mechanical study of hydrogels and an organogel as potential synthetic brain phantom
School Name
Governor's School for Science and Mathematics
Grade Level
12th Grade
Presentation Topic
Engineering
Presentation Type
Mentored
Written Paper Award
1st Place
Abstract
The brain is an intricate organ, composed of white matter, gray matter, blood vessels, nerves, and dura matter. The study and surgical intervention of the brain is limited by the availability of cadavers for research and experience in the operating room. This work proposes the use of a 3D phantom brain tissue to create a realistic model of the brain with accurate mechanical properties of the brain. In particular, this study assess the mechanical properties of synthetic materials and porcine brain and tests properties of stress, strain, relaxation, and adhesion. Gelatin-based hydrogels and oil-based emulsions served as the two candidates for a brain substitute material. Results demonstrate that 1.7% Chromium 3.5% Gelatin was more similar to porcine brain in compression properties as shown by compression stress strain analysis and the other properties. This study has found a viable material substitute for the fabrication of a 3D brain phantom that aims to improve the learning experience of medical students and the preoperative planning of surgeons.
Recommended Citation
Troup, Allison, "The mechanical study of hydrogels and an organogel as potential synthetic brain phantom" (2018). South Carolina Junior Academy of Science. 54.
https://scholarexchange.furman.edu/scjas/2018/all/54
Location
Neville 109
Start Date
4-14-2018 9:30 AM
Presentation Format
Oral and Written
The mechanical study of hydrogels and an organogel as potential synthetic brain phantom
Neville 109
The brain is an intricate organ, composed of white matter, gray matter, blood vessels, nerves, and dura matter. The study and surgical intervention of the brain is limited by the availability of cadavers for research and experience in the operating room. This work proposes the use of a 3D phantom brain tissue to create a realistic model of the brain with accurate mechanical properties of the brain. In particular, this study assess the mechanical properties of synthetic materials and porcine brain and tests properties of stress, strain, relaxation, and adhesion. Gelatin-based hydrogels and oil-based emulsions served as the two candidates for a brain substitute material. Results demonstrate that 1.7% Chromium 3.5% Gelatin was more similar to porcine brain in compression properties as shown by compression stress strain analysis and the other properties. This study has found a viable material substitute for the fabrication of a 3D brain phantom that aims to improve the learning experience of medical students and the preoperative planning of surgeons.
