Using a Machine Learning Algorithm to Detect Basal Cell Carcinoma in Microscope Slides of Mohs Excisions

Author(s)

Luke ZhangFollow

School Name

Spring Valley High School

Grade Level

11th Grade

Presentation Topic

Computer Science

Presentation Type

Non-Mentored

Written Paper Award

1st Place

Abstract

It has been estimated that approximately 20% of Americans will develop some form of skin cancer in their lifetime; over 80% of these cases will be basal cell carcinoma. The process of detecting and locating basal cell carcinoma in microscope slides of Mohs excisions is time-consuming for Mohs surgeons, and operations can take hours to complete. Machine learning is a new field of artificial intelligence that has started to see growth in the field of medicine over the past few years. This experiment was conducted in order to study how accurately a supervised machine learning program would be able to detect the presence of basal cell carcinoma in microscope slides of Mohs excisions. It was hypothesized that the algorithm, after training, would be able to detect examples of basal cell carcinoma at an accuracy rate of 95% or higher. There were 1660 slides in total, with 1490 being used for the training period and the final 170 for testing. The final model was trained for 5 hours and had an average precision of 0.995. The precision and recall values were both 0.976 at a score threshold of 0.5.

Location

Founders Hall 140 B

Start Date

3-30-2019 9:45 AM

Presentation Format

Oral and Written

Group Project

No

COinS
 
Mar 30th, 9:45 AM

Using a Machine Learning Algorithm to Detect Basal Cell Carcinoma in Microscope Slides of Mohs Excisions

Founders Hall 140 B

It has been estimated that approximately 20% of Americans will develop some form of skin cancer in their lifetime; over 80% of these cases will be basal cell carcinoma. The process of detecting and locating basal cell carcinoma in microscope slides of Mohs excisions is time-consuming for Mohs surgeons, and operations can take hours to complete. Machine learning is a new field of artificial intelligence that has started to see growth in the field of medicine over the past few years. This experiment was conducted in order to study how accurately a supervised machine learning program would be able to detect the presence of basal cell carcinoma in microscope slides of Mohs excisions. It was hypothesized that the algorithm, after training, would be able to detect examples of basal cell carcinoma at an accuracy rate of 95% or higher. There were 1660 slides in total, with 1490 being used for the training period and the final 170 for testing. The final model was trained for 5 hours and had an average precision of 0.995. The precision and recall values were both 0.976 at a score threshold of 0.5.