Effects of Silver Nanoparticles on Mice Health

Justin Thomas

Abstract

Silver Nanoparticles are one of the most commonly used nanotechnologies, and they are put into many different consumer products. Currently, there is more literature regarding the utilization, characterization, and impact of AgNPs in comparison to other engineered nanomaterials. However, the adverse risk effects associated with exposure to AgNPs is still partly unknown. The aim of this project is to further investigate the risk of AgNPs regarding their toxicity in mammalian cells within the reproductive system, liver, spleen, kidney, and heart of female mice. 21 day old, CD1 mice were injected with or without AgNPs solution at a dosage of 0.2 mg/kg per day for seven days. After the period of injections, tissue samples were taken from the mice and placed into slides to be examined under a microscope. The histology of the tissues from the treatment group, when compared to that of the control group, did not show any signs of adverse effects from the AgNPs. This implies that exposure to AgNPs does not cause any adverse effects when the duration of exposure remains relatively short.

 
Mar 30th, 9:30 AM

Effects of Silver Nanoparticles on Mice Health

Founders Hall 213 B

Silver Nanoparticles are one of the most commonly used nanotechnologies, and they are put into many different consumer products. Currently, there is more literature regarding the utilization, characterization, and impact of AgNPs in comparison to other engineered nanomaterials. However, the adverse risk effects associated with exposure to AgNPs is still partly unknown. The aim of this project is to further investigate the risk of AgNPs regarding their toxicity in mammalian cells within the reproductive system, liver, spleen, kidney, and heart of female mice. 21 day old, CD1 mice were injected with or without AgNPs solution at a dosage of 0.2 mg/kg per day for seven days. After the period of injections, tissue samples were taken from the mice and placed into slides to be examined under a microscope. The histology of the tissues from the treatment group, when compared to that of the control group, did not show any signs of adverse effects from the AgNPs. This implies that exposure to AgNPs does not cause any adverse effects when the duration of exposure remains relatively short.