The Relationship between Age-related Speech Disfluencies and Life Satisfaction in Mothers with FMR1 Premutation

School Name

Ridge View High School

Grade Level

11th Grade

Presentation Topic

Psychology

Presentation Type

Mentored

Abstract

Fragile X Syndrome (FXS) is a genetic disorder that is caused by a gene mutation in the CGG repeat DNA segment within the Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene. There are three main variations of FXS: intermediate, premutation (FXpm), and full mutation. People with FXpm, have shown an increased amount of speech disfluencies. Previous studies have shown that people with FXpm are more prone to developing speech-related disorders, compared to typical-developing people. While FXS affects mostly males, it still affects females, just with higher variable severity. This experiment was conducted to investigate the relationship between speech disfluencies and life satisfaction in mothers with FMR1 Premutation. A major finding revealed in this experiment was that mothers with the FXpm did show a lower average life satisfaction score, compared to typical-developing mothers. In addition, there was a high association between repetitions and lower life satisfaction scores in typical-developing mothers. These results revealed that higher speech disfluencies, especially repetitions, can lead to lower life satisfaction. Furthermore, mothers with FXpm may show lower life satisfaction than typical-developing mothers.

Location

RITA 261

Start Date

3-23-2024 10:15 AM

Presentation Format

Oral and Written

Group Project

No

COinS
 
Mar 23rd, 10:15 AM

The Relationship between Age-related Speech Disfluencies and Life Satisfaction in Mothers with FMR1 Premutation

RITA 261

Fragile X Syndrome (FXS) is a genetic disorder that is caused by a gene mutation in the CGG repeat DNA segment within the Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene. There are three main variations of FXS: intermediate, premutation (FXpm), and full mutation. People with FXpm, have shown an increased amount of speech disfluencies. Previous studies have shown that people with FXpm are more prone to developing speech-related disorders, compared to typical-developing people. While FXS affects mostly males, it still affects females, just with higher variable severity. This experiment was conducted to investigate the relationship between speech disfluencies and life satisfaction in mothers with FMR1 Premutation. A major finding revealed in this experiment was that mothers with the FXpm did show a lower average life satisfaction score, compared to typical-developing mothers. In addition, there was a high association between repetitions and lower life satisfaction scores in typical-developing mothers. These results revealed that higher speech disfluencies, especially repetitions, can lead to lower life satisfaction. Furthermore, mothers with FXpm may show lower life satisfaction than typical-developing mothers.